Cardiovascular disease (CVD) remains a major public health problem in Sweden. Area of residence has been suggested to increase the risk of CVD and CVD specific mortality in the general population but less investigated in adults with type 1 diabetes mellitus.
The aim is to deepen knowledge on health inequalities at area level by assessing whether the risk of incident CVD and CVD specific mortality among adults with type 1 diabetes mellitus living in disadvantaged areas differed from those in other areas of Stockholm County. Therefore, a cohort study in which 7544 adults with type 1 diabetes mellitus aged 40-80 years, living in disadvantaged and other areas of Stockholm County in 2006 were followed from 2006-2011. Crude and adjusted hazard ratios for incident CVD and CVD specific mortality were calculated using Cox proportional hazard regression. All models were adjusted for age, gender, education, country of birth, social allowance, disability allowance and disposable income.
Results: Adjusted hazard ratios for CVD, stroke, peripheral vascular disease, myocardial infarction and CVD specific mortality were 1.2 (95% CI 0.5-2.0), 1.2 (95% CI 0.6-3.1), 1.0 (95% CI 0.5-2.9), 1.9 (95% CI 1.07-3.6) and 1.3 (95% CI 0.5-4.5) respectively for subjects in disadvantaged areas compared to other areas of Stockholm County.
Inhaltsverzeichnis (Table of Contents)
- 1 Background
- 1.1 Area of residence
- 1.2 Area of residence and risk of CVD in adults with T1DM
- 1.3 Area of residence and risk of cardiovascular disease specific mortality in adults with T1DM
- 2 Aim and research questions
- 2.1 Aim
- 2.2 Research Questions
- 3 Materials and methods
- 3.1 Study design and population
- 3.2 Data Sources
- 3.3 Study setting
- 3.4 Exposure
- 3.5 Covariates
- 3.6 Outcomes
- 4 Statistical analysis
- 5 Ethical Considerations
- 6 Results
- 6.1 Socio-demographic characteristics of adults with type 1 diabetes mellitus
- 6.2 Risk of incident CVD, stroke, myocardial infarction and peripheral vascular disease according to area of residence.
- 6.3 Risk of CVD specific mortality according to area of residence
- 7 Discussion
- 8 Strengths and limitations
- 9 Conclusion and implications
- 10 Acknowledgment
- 11 Reference
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This study investigates the relationship between area of residence and the risk of cardiovascular disease (CVD) and CVD-specific mortality among adults with type 1 diabetes mellitus (T1DM) in Stockholm County, Sweden. The primary objective is to assess whether adults living in disadvantaged areas experience an increased risk compared to those residing in other areas.
- Health inequalities at area level
- The impact of area of residence on CVD risk in individuals with T1DM
- Socio-demographic factors influencing CVD risk
- Comparison of CVD incidence and mortality between disadvantaged and other areas
- Public health implications of findings
Zusammenfassung der Kapitel (Chapter Summaries)
The study begins by outlining the background of CVD as a significant public health concern in Sweden and exploring previous research on the association between area of residence and CVD risk, particularly in adults with T1DM. The aim and research questions are then clearly stated. The methodology section details the study design, data sources, study setting, exposure, covariates, and outcomes. Statistical analysis methods are also described. The study's ethical considerations are discussed, followed by a presentation of the results, including socio-demographic characteristics of the study population and the association between area of residence and CVD risk and mortality. The discussion section interprets the findings, while the strengths and limitations of the study are critically evaluated. Finally, the conclusion and implications for public health are summarized.
Schlüsselwörter (Keywords)
The primary keywords and focus topics of the text include area of residence, cardiovascular disease, stroke, myocardial infarction, peripheral vascular disorders, mortality, morbidity, type 1 diabetes mellitus, health inequalities, and Swedish cohort study.
- Citar trabajo
- Ratib Mawa (Autor), 2016, Area of residence and risk of cardiovascular disease and mortality among adults with type 1 diabetes mellitus in Stockholm County, Múnich, GRIN Verlag, https://www.grin.com/document/387175
